Journal article icon

Journal article

Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR.

Abstract:

Most cancer genomes are characterized by the gain or loss of copies of some sequences through deletion, amplification or unbalanced translocations. Delineating and quantifying these changes is important in understanding the initiation and progression of cancer, in identifying novel therapeutic targets, and in the diagnosis and prognosis of individual patients. Conventional methods for measuring copy-number are limited in their ability to analyse large numbers of loci, in their dynamic range a...

Expand abstract

Actions


Access Document


Publisher copy:
10.1002/path.2413

Authors


Expand authors...
Journal:
Journal of pathology
Volume:
216
Issue:
3
Pages:
307-316
Publication date:
2008-11-01
DOI:
EISSN:
1096-9896
ISSN:
0022-3417
Source identifiers:
324315
Language:
English
Keywords:
Pubs id:
pubs:324315
UUID:
uuid:d7355a5a-6a2b-4af2-8bb4-ea32234f63f0
Local pid:
pubs:324315
Deposit date:
2013-11-16

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP