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Stochastic sensing of polynucleotides using patterned nanopores

Abstract:

The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the translocation process is extremely sensitive to the detailed structure of such patterns with faster than exponential dependence of translocation times on the stickiness of the pore. The stochastic nature of the translocation process leads to discernable differences...

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Publication status:
Published

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Publisher copy:
10.1103/PhysRevX.2.021002

Authors


Chaudhuri, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Theoretical Physics
Journal:
Phys. Rev. X
Volume:
2
Issue:
2
Pages:
021002
Publication date:
2012-01-21
DOI:
EISSN:
2160-3308
ISSN:
2160-3308
URN:
uuid:d724fc94-1358-4d1c-b206-f65bb6ab89ec
Source identifiers:
254316
Local pid:
pubs:254316
Language:
English
Keywords:

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