- Abstract:
-
1 The beta-adrenoceptor agonist, isoprenaline (1.5-3.0 mg kg(-1) intravenously), produced a dose-related increase in rat pineal melatonin content. This increase was prevented by pretreatment with the selective beta(1)-adrenoceptor antagonist, atenolol (2 mg kg(-1)), but not by the beta(2)-adrenoceptor antagonist, butoxamine (2 mg kg(-1)). The beta(2)-adrenoceptor agonist, terbutaline (5.0 mg kg(-1)), produced a moderate increase in pineal melatonin content.2 Repeated daily administration of d...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1476-5381.1983.tb09367.x
-
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- Journal:
- British journal of pharmacology
- Volume:
- 78
- Issue:
- 1
- Pages:
- 89-96
- Publication date:
- 1983-01-05
- DOI:
- EISSN:
-
1476-5381
- ISSN:
-
0007-1188
- URN:
-
uuid:d71baa33-1873-40bf-b7ab-68f0520d603e
- Source identifiers:
-
185959
- Local pid:
- pubs:185959
- Copyright date:
- 1983
Journal article
The effect of chronic antidepressant administration on beta-adrenoceptor function of the rat pineal.
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