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Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand.

Abstract:

BACKGROUND: The use of artemisinin derivatives has increased exponentially with the deployment of artemisinin combination therapy (ACT) in all malarious areas. They are highly effective and are considered safe, but in animal studies artemisinin derivatives produce neurotoxicity targeting mainly the auditory and vestibular pathways. The debate remains as to whether artemisinin derivatives induce similar toxicity in humans. METHODS: This prospective study assessed the effects on auditory funct...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1475-2875-7-233

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Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Malaria Journal Journal website
Volume:
7
Issue:
1
Pages:
Article: 233
Publication date:
2008-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:d70c5aec-5d77-4217-a4dd-ff0d05654365
Source identifiers:
19024
Local pid:
pubs:19024

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