- Abstract:
-
BACKGROUND AND PURPOSE: Addition of carbogen and nicotinamide (hypoxia-modifying agents) to radiotherapy improves the survival of patients with high risk bladder cancer. The study investigated whether histopathological tumour features and putative hypoxia markers predicted benefit from hypoxia modification. MATERIALS AND METHODS: Samples were available from 231 patients with high grade and invasive bladder carcinoma from the BCON phase III trial of radiotherapy (RT) alone or with carbogen and...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.radonc.2013.05.017
-
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- Journal:
- Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
- Volume:
- 108
- Issue:
- 1
- Pages:
- 40-47
- Publication date:
- 2013-07-05
- DOI:
- EISSN:
-
1879-0887
- ISSN:
-
0167-8140
- URN:
-
uuid:d701436d-8ba0-4988-b0df-1d39d7de0bfe
- Source identifiers:
-
405914
- Local pid:
- pubs:405914
- Copyright date:
- 2013
Journal article
Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial.
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