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Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Abstract:

Height is a classic complex trait with common variants in a growing list of genes known to contribute to the phenotype. Using a genecentric genotyping array targeted toward cardiovascular-related loci, comprising 49,320 SNPs across approximately 2000 loci, we evaluated the association of common and uncommon SNPs with adult height in 114,223 individuals from 47 studies and six ethnicities. A total of 64 loci contained a SNP associated with height at array-wide significance (p < 2.4 × 10(-6)...

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Publication status:
Published

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Publisher copy:
10.1016/j.ajhg.2010.11.007

Authors


Lanktree, MB More by this author
Murtaza, M More by this author
Glessner, JT More by this author
Bailey, SD More by this author
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Journal:
American journal of human genetics
Volume:
88
Issue:
1
Pages:
6-18
Publication date:
2011-01-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:d6fa56e3-4f19-4c84-b96f-c4f6579a4df7
Source identifiers:
110198
Local pid:
pubs:110198

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