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Pathogenic autoantibodies to neuronal proteins in neurological disorders.

Abstract:

Autoantibodies to acetylcholine receptors and to voltage-gated calcium and potassium channels are thought to be pathogenic in three peripheral neurological disorders: myasthenia gravis, the Lambert Eaton syndrome and acquired neuromyotonia. However, evidence for the role of antibodies in conditions involving the central nervous system, is scanty or unclear. This review describes the ways in which the roles of autoantibodies have been defined in the peripheral diseases, and discusses the more ...

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Publication status:
Published

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Authors


Vincent, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
Journal of neuroimmunology
Volume:
100
Issue:
1-2
Pages:
169-180
Publication date:
1999-12-05
DOI:
EISSN:
1872-8421
ISSN:
0165-5728
URN:
uuid:d6f28dad-987f-41b0-b8fb-a77b7b713ace
Source identifiers:
387043
Local pid:
pubs:387043

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