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Serum matrix metalloproteinase 9 and colorectal neoplasia: A community-based evaluation of a potential diagnostic test

Abstract:

Background: A blood test may be a more acceptable routine colorectal cancer (CRC) screening test than faecal occult blood test, flexible sigmoidoscopy or colonoscopy, and could be safer and cheaper. We evaluated the accuracy of a serum matrix metalloproteinase (MMP9) test for CRC in a non-presenting symptomatic population. Methods: A cohort, aged 50-69 with lower gastrointestinal symptoms, was identified by community-based survey. Accuracy of serum MMP9 was assessed by comparison with colonos...

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Publisher copy:
10.1038/bjc.2012.93

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Journal:
British Journal of Cancer
Volume:
106
Issue:
8
Pages:
1431-1438
Publication date:
2012-04-10
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:d6ef12fe-da2a-4e7c-b715-5772acea1252
Source identifiers:
325328
Local pid:
pubs:325328

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