Journal article
EGAD! There is an ERAD doppelganger in the Golgi
- Abstract:
- Disposal of membrane proteins in the late secretory pathway is thought to be exclusively facilitated by ESCRT‐dependent lysosomal degradation. In this issue of The EMBO Journal, Schmidt et al define a previously uncharacterized endosome and Golgi‐associated degradation (EGAD) pathway. This pathway, which has remarkable similarities to ERAD in the endoplasmic reticulum, operates in post‐ER organelles via the proteasome and contributes to lipid homeostasis in eukaryotic cells.
- Publication status:
- Published
- Peer review status:
- Reviewed (other)
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- Files:
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(Accepted manuscript, pdf, 107.4KB)
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- Publisher copy:
- 10.15252/embj.2019102679
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Authors
Bibliographic Details
- Publisher:
- EMBO Press Publisher's website
- Journal:
- EMBO Journal Journal website
- Volume:
- 38
- Issue:
- 15
- Article number:
- e102679
- Publication date:
- 2019-07-22
- Acceptance date:
- 2019-07-03
- DOI:
- EISSN:
-
1460-2075
- ISSN:
-
0261-4189
- Pmid:
-
31328805
- Source identifiers:
-
1035625
Item Description
- Language:
- English
- Pubs id:
-
pubs:1035625
- UUID:
-
uuid:d6cad8fb-149c-42e3-be7e-116861dae711
- Local pid:
- pubs:1035625
- Deposit date:
- 2019-08-10
Terms of use
- Copyright holder:
- Fonseca and Carvalho
- Copyright date:
- 2019
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