Journal article icon

Journal article

EGAD! There is an ERAD doppelganger in the Golgi

Abstract:
Disposal of membrane proteins in the late secretory pathway is thought to be exclusively facilitated by ESCRT‐dependent lysosomal degradation. In this issue of The EMBO Journal, Schmidt et al define a previously uncharacterized endosome and Golgi‐associated degradation (EGAD) pathway. This pathway, which has remarkable similarities to ERAD in the endoplasmic reticulum, operates in post‐ER organelles via the proteasome and contributes to lipid homeostasis in eukaryotic cells.
Publication status:
Published
Peer review status:
Reviewed (other)

Actions


Access Document


Files:
Publisher copy:
10.15252/embj.2019102679

Authors


More by this author
Institution:
University of Oxford
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Lincoln College
Role:
Author
ORCID:
0000-0002-9691-5277
Publisher:
EMBO Press Publisher's website
Journal:
EMBO Journal Journal website
Volume:
38
Issue:
15
Article number:
e102679
Publication date:
2019-07-22
Acceptance date:
2019-07-03
DOI:
EISSN:
1460-2075
ISSN:
0261-4189
Pmid:
31328805
Source identifiers:
1035625
Language:
English
Pubs id:
pubs:1035625
UUID:
uuid:d6cad8fb-149c-42e3-be7e-116861dae711
Local pid:
pubs:1035625
Deposit date:
2019-08-10

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP