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Journal article

Large-scale fine mapping of the HNF1B locus and prostate cancer risk.

Abstract:

Previous genome-wide association studies have identified two independent variants in HNF1B as susceptibility loci for prostate cancer risk. To fine-map common genetic variation in this region, we genotyped 79 single nucleotide polymorphisms (SNPs) in the 17q12 region harboring HNF1B in 10 272 prostate cancer cases and 9123 controls of European ancestry from 10 case-control studies as part of the Cancer Genetic Markers of Susceptibility (CGEMS) initiative. Ten SNPs were significantly related t...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddr213

Authors


Berndt, SI More by this author
Sampson, J More by this author
Jacobs, KB More by this author
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Journal:
Human molecular genetics
Volume:
20
Issue:
16
Pages:
3322-3329
Publication date:
2011-08-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:d6c745a9-426f-43e4-a0c2-870d2c1d2260
Source identifiers:
170234
Local pid:
pubs:170234

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