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Thesis

Aspects of nucleic acid metabolism during nutritional deficiency in Escherchia coli

Abstract:

This thesis concerns an investigation of the effects of thymine deficiency in thymineless mytants of Escherichia coli. Evidence was available which implicated damage to the DNA of the cell as the cause of the loss of viability (thymineless death) which accompanies thymine deficiency. DNA has been extracted from bacteria before and after thymineless death and examined for chemical and physical differences. There was evidence that the DNA extracted after thymineless death was labile ...

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Peer review status:
Peer reviewed

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Department:
University of Oxford
Role:
Author
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Source identifiers:
601870793
UUID:
uuid:d6bfb845-dab2-4a8f-88ef-d93b417b804f
Local pid:
polonsky:13:11
Deposit date:
2017-10-05

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