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Thesis

Enantioselective synthesis of chiral building blocks with non-stabilized nucleophiles

Abstract:

This thesis describes the combination of non-stabilized nucleophiles and prochiral/racemic electrophiles in transition metal catalyzed asymmetric transformations. These enantioselective reactions have tremendous potential for the formation of chiral building blocks and new structural motifs that can be found in a variety of natural products and their derivatives.

The first part of the thesis focuses on the synthetic approach towards anti-cancer active diterpenoid structures. The two...

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Philipp Schäfer More by this author

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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