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Acromegaly and anaplastic astrocytoma: coincidence or pathophysiological relation?

Abstract:

Insulin-like growth factor type I (IGF-I) is an important promoter in the tumorigenesis of several extracranial and intracranial neoplasms. In astrocytic-cell tumors, the role of autocrine and paracrine IGF-I expression in enhancing tumoral progression is well established. However, the influence of systemic IGF-I levels on the clinical behavior of astrocytic neoplasms remains an open subject of research. We report the case of a 28-year-old man who presented simultaneously with acromegaly and ...

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Publication status:
Published

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Publisher copy:
10.1007/s11102-007-0074-2

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Pituitary
Volume:
11
Issue:
3
Pages:
325-330
Publication date:
2008-01-01
DOI:
EISSN:
1573-7403
ISSN:
1386-341X
URN:
uuid:d69cc1b9-d4e5-46fb-949c-f16046ce3521
Source identifiers:
29316
Local pid:
pubs:29316

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