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Rectal pH in well and unwell infants.

Abstract:

Prompt antibiotic treatment for infants with sepsis has the potential to save lives. A rectal formulation of an antibiotic could be used at a village level before referral to hospital. The development of such a preparation needs to take into account the rectal pH of infants that will affect drug partitioning and absorption. Rectal pH measurements were taken in 100 well and 45 unwell infants. We also measured rectal pH in 14 infants sequentially over the course of their illness. The mean recta...

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Publication status:
Published

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Publisher copy:
10.1093/tropej/fmr088

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
Journal of tropical pediatrics
Volume:
58
Issue:
4
Pages:
311-313
Publication date:
2012-08-05
DOI:
EISSN:
1465-3664
ISSN:
0142-6338
URN:
uuid:d69a11c5-60d0-4917-9e6c-9f5a6407bb5a
Source identifiers:
186642
Local pid:
pubs:186642

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