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Journal article

Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial.

Abstract:

BACKGROUND: Chromosomal abnormalities in childhood acute lymphoblastic leukaemia are well established disease markers and indicators of outcomes. However, the long-term prognosis and independent prognostic effect of some abnormalities has been questioned. Also, little is known about the association between cytogenetics and the characteristics of relapse (eg, time and site of relapse) that are known to predict outcome after relapse. METHODS: We analysed cytogenetic data from 1725 children with...

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Publication status:
Published

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Journal:
Lancet. Oncology
Volume:
11
Issue:
5
Pages:
429-438
Publication date:
2010-05-01
DOI:
EISSN:
1474-5488
ISSN:
1470-2045
Source identifiers:
60683
Language:
English
Keywords:
Pubs id:
pubs:60683
UUID:
uuid:d69636ef-a547-45e8-bca5-0c4bc1045d1a
Local pid:
pubs:60683
Deposit date:
2012-12-19

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