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Tetrachlorophthalic anhydride asthma: evidence for specific IgE antibody

Abstract:

We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlorophthalic anhydride (TCPA), an epoxy resin hardening agent. Inhalation tests with TCPA at atmospheric concentrations of less than one tenth of a manufacturer's recommended exposure limit provoked asthmatic reactions in the four women tested. None had evidence of pretest bronchial hyperreactivity. Immediate skin prick test reactions were elicited in the seven subjects by a conjugate of TCPA wit...

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author
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Journal:
Journal of Allergy and Clinical Immunology
Volume:
71
Issue:
1 PART 1
Pages:
5-11
Publication date:
1983-01-01
DOI:
ISSN:
0091-6749
Source identifiers:
351692
Language:
English
Pubs id:
pubs:351692
UUID:
uuid:d691bed0-7607-404d-9acd-2cf3e8bad36c
Local pid:
pubs:351692
Deposit date:
2012-12-19

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