Journal article
Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.
- Abstract:
-
Type I interferon (IFN) is crucial during infection through its antiviral properties and by coordinating the immunocompetent cells involved in antiviral or antibacterial immunity. Type I IFN (IFN-α and IFN-β) is produced after virus or bacteria recognition by cytosolic receptors or membrane-bound TLR receptors following the activation of the transcription factors IRF3 or IRF7. IFN-β production after fungal infection was recently reported, although the underlying mechanism remains controversia...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.immuni.2013.05.010
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Bibliographic Details
- Journal:
- Immunity
- Volume:
- 38
- Issue:
- 6
- Pages:
- 1176-1186
- Publication date:
- 2013-06-01
- DOI:
- EISSN:
-
1097-4180
- ISSN:
-
1074-7613
- Source identifiers:
-
406429
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:406429
- UUID:
-
uuid:d690fb43-1b89-4c11-8bb1-da214766448a
- Local pid:
- pubs:406429
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2013
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