Journal article
Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data
- Abstract:
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BACKGROUND:Pneumococcal conjugate vaccines (PCV) have reduced pneumococcal diseases globally. Pneumococcal genomic surveys elucidate PCV effects on population structure but are rarely conducted in low-income settings despite the high disease burden. METHODS:We undertook whole genome sequencing of 660 pneumococcal isolates collected through surveys from healthy carriers two years from PCV14 introduction and one-year post-rollout in northern Malawi. We investigated changes in population structu...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 28.3MB, Terms of use)
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- Publisher copy:
- 10.1093/cid/ciz404
Authors
Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Clinical Infectious Diseases More from this journal
- Volume:
- 70
- Issue:
- 7
- Pages:
- 1294–1303
- Publication date:
- 2019-05-16
- DOI:
- EISSN:
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1537-6591
- ISSN:
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1058-4838
- Pmid:
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31094423
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:999241
- UUID:
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uuid:d682ed95-719f-4363-afa3-c930e893a8c5
- Local pid:
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pubs:999241
- Source identifiers:
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999241
- Deposit date:
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2019-05-30
Terms of use
- Copyright holder:
- Chaguza et al
- Copyright date:
- 2019
- Notes:
- © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited
- Licence:
- CC Attribution (CC BY)
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