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Journal article

Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children.

Abstract:

BACKGROUND: In the USA, most HIV-1 infected children are on antiretroviral drug regimens, with many individuals surviving through adolescence and into adulthood. The course of HIV-1 infection in these children is variable, and understudied. METHODOLOGY/PRINCIPAL FINDINGS: We determined whether qualitative differences in immune cell subsets could explain a slower disease course in long term survivors with no evidence of immune suppression (LTS-NS; CD4%≥25%) compared to those with severe immun...

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10.1371/journal.pone.0029154

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
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Journal:
PloS one
Volume:
7
Issue:
1
Pages:
e29154
Publication date:
2012-01-01
DOI:
EISSN:
1932-6203
URN:
uuid:d6621a43-2bec-4083-a2a3-624524ee0f0f
Source identifiers:
237081
Local pid:
pubs:237081

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