- Abstract:
-
Virus-specific CD8+ T cell responses play an important role in the natural course of infection; however, the impact of certain CD8+ T cell responses in determining clinical outcome has not been fully defined. A well-defined cohort of women inoculated with HCV from a single source showed that HLA-B27 has a strong association with spontaneous clearance. The immunological basis for this association is unknown. However, the finding is especially significant because HLA-B27 has also been shown to ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/hep.21049
-
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- Journal:
- Hepatology (Baltimore, Md.)
- Volume:
- 43
- Issue:
- 3
- Pages:
- 563-572
- Publication date:
- 2006-03-05
- DOI:
- EISSN:
-
1527-3350
- ISSN:
-
0270-9139
- URN:
-
uuid:d63b5fdc-ac2b-4ba8-b45d-399bdb139e4d
- Source identifiers:
-
23509
- Local pid:
- pubs:23509
- Copyright date:
- 2006
Journal article
Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.
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