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Journal article

Age of onset in concordant twins and other relative pairs with multiple sclerosis.

Abstract:

The ages of onset in multiple sclerosis cases span more than 7 decades. Data are presented for affected relative pairs from a Canadian population base of 30,000 multiple sclerosis index cases (1993-2008). The effects of genetic sharing, parent of origin, intergenerational versus collinear differences, and gender on the ages of onset were evaluated in the following concordant pairs: monozygotic twins (n = 29), dizygotic twins (n = 10), siblings (n = 614), first cousins (n = 405), half siblings...

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Publication status:
Published

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Publisher copy:
10.1093/aje/kwp143

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Journal:
American journal of epidemiology
Volume:
170
Issue:
3
Pages:
289-296
Publication date:
2009-08-05
DOI:
EISSN:
1476-6256
ISSN:
0002-9262
URN:
uuid:d635981c-8113-4fc9-bf6b-55879da62c2e
Source identifiers:
34769
Local pid:
pubs:34769

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