Journal article
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.
- Abstract:
-
Neutrophil lifespan and function are regulated by hypoxia via components of the hypoxia inducible factor (HIF)/von Hippel Lindau/hydroxylase pathway, including specific roles for HIF-1α and prolyl hydroxylase-3. HIF-2α has both distinct and overlapping biological roles with HIF-1α and has not previously been studied in the context of neutrophil biology. We investigated the role of HIF-2α in regulating key neutrophil functions. Human and murine peripheral blood neutrophils expressed HIF-2α, wi...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- American Society of Hematology
- Journal:
- Blood More from this journal
- Volume:
- 123
- Issue:
- 3
- Pages:
- 366-376
- Publication date:
- 2014-01-16
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:438855
- UUID:
-
uuid:d61de947-9bdb-4384-af86-39f952d508fc
- Local pid:
-
pubs:438855
- Source identifiers:
-
438855
- Deposit date:
-
2014-02-17
Terms of use
- Copyright holder:
- American Society of Hematology
- Copyright date:
- 2014
- Notes:
- © 2014 by The American Society of Hematology. We are not permitted to provide the full text of this article at this time.
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record