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Journal article

Comparative analysis of the alpha-like globin clusters in mouse, rat, and human chromosomes indicates a mechanism underlying breaks in conserved synteny.

Abstract:

We have sequenced and fully annotated a 65,871-bp region of mouse Chromosome 17 including the Hba-ps4 alpha-globin pseudogene. Comparative sequence analysis with the functional alpha-globin loci at human Chromosome 16p13.3 and mouse Chromosome 11 shows that this segment of mouse Chromosome 17 contains a group of three alpha-like pseudogenes (Hba-psm-Hba-ps4-Hba-q3), similar to the duplicated sets found at the functional mouse cluster on Chromosome 11. In addition, exons 7 to 12 of the mLuc7L ...

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Publication status:
Published

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Publisher copy:
10.1101/gr.2143604

Authors


Tufarelli, C More by this author
Hardison, R More by this author
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Journal:
Genome research
Volume:
14
Issue:
4
Pages:
623-630
Publication date:
2004-04-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:d6160a4e-d72e-4318-a29f-e530fcc7f5fb
Source identifiers:
55948
Local pid:
pubs:55948

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