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Concise, stereoselective syntheses of cis-nemorensic acid and 4-hydroxy-cis-nemorensic acid via tandem carbonyl ylide formation-cycloaddition.

Abstract:
[reaction: see text] 1,3-Dipolar cycloaddition of propargyl bromide with the carbonyl ylide derived from 6-diazoheptane-2,5-dione is the key step in concise syntheses of cis-nemorensic acid and 4-hydroxy-cis-nemorensic acid.
Publication status:
Published

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Publisher copy:
10.1021/ol025917c

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Organic letters
Volume:
4
Issue:
10
Pages:
1809-1811
Publication date:
2002-05-05
DOI:
EISSN:
1523-7052
ISSN:
1523-7060
URN:
uuid:d5e7e643-28b4-462c-858d-ba94831caef7
Source identifiers:
32105
Local pid:
pubs:32105

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