Journal article
Iridium-catalyzed C4-alkylation of 2,6-di-tert-butylphenol by using hydrogen-borrowing catalysis
- Abstract:
- An iridium-catalyzed hydrogen borrowing process has been developed whereby 2,6-di-tert-butylphenol can be alkylated at the C4-position using a range of different primary alcohols (11 examples, 40–93% yield). Following this, a selection of the products obtained underwent retroFriedel–Crafts reaction to provide para-substituted phenols which could potentially undergo further synthetic manipulation.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 230.3KB, Terms of use)
-
- Publisher copy:
- 10.1055/s-0035-1561439
Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Frost, J
Donohoe, T
Grant:
EP/L023121/1
EP/L023121/1
Bibliographic Details
- Publisher:
- Thieme
- Journal:
- Synthesis More from this journal
- Volume:
- 49
- Issue:
- 4
- Pages:
- 910-916
- Publication date:
- 2016-05-01
- Acceptance date:
- 2016-04-02
- DOI:
- EISSN:
-
1437-210X
- ISSN:
-
0039-7881
Item Description
- Keywords:
- Pubs id:
-
pubs:624008
- UUID:
-
uuid:d5a23fac-f11f-4924-9625-4a89b10e4b59
- Local pid:
-
pubs:624008
- Source identifiers:
-
624008
- Deposit date:
-
2016-07-08
Terms of use
- Copyright holder:
- Georg Thieme Verlag
- Copyright date:
- 2016
- Notes:
- © Georg Thieme Verlag Stuttgart · New York — Synthesis 2016, 48, A–G. This is the publisher version of the article. The final version is available online from Thieme at: https://doi.org/10.1055/s-0035-1561439
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record