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Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke.

Abstract:

BACKGROUND AND PURPOSE: In acute ischemic stroke, the amount of neuronal damage in hyperintense areas on MR diffusion imaging (DWI) is unclear. We used spectroscopic imaging to measure N-acetyl aspartate (NAA, a marker of normal neurons) and lactate (a marker of ischemia) to compare with diffusion and perfusion values in the diffusion lesion in acute ischemic stroke. METHODS: We recruited patients with acute ischemic stroke prospectively and performed MR diffusion weighted (DWI), perfusion, ...

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Publication status:
Published

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Journal:
Stroke; a journal of cerebral circulation
Volume:
40
Issue:
3
Pages:
767-772
Publication date:
2009-03-05
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
URN:
uuid:d59eeeeb-f7a4-444f-805d-8681ac53ccce
Source identifiers:
226415
Local pid:
pubs:226415

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