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Thesis

An investigation of T cell immunity and the HIV reservoir during primary HIV infection: implications for cure strategies

Abstract:

This work focuses on aspects of T cell immunity during the early stages of human immunodeficiency virus (HIV) infection, termed primary infection. Individuals who commence antiretroviral therapy (ART) during primary infection may have preserved immune function, making them a target group for curative strategies. The efficacy of HIV cure interventions are assessed by stopping ART and measuring how long it takes until plasma viraemia recurs. Here, the normal dynamics of this viral rebound in...

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Department:
Nuffield Department of Medicine
Role:
Author

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Department:
Nuffield Department of Medicine
Role:
Supervisor
Department:
Nuffield Department of Medicine
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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