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Journal article

The contribution of HLA genes to IBD susceptibility and phenotype.

Abstract:

The human leukocyte antigen (HLA) region located on chromosome 6p encodes the highly polymorphic, classical class I and II genes essential for normal lymphocyte function; it also encodes a further 224 genes. Many early studies investigating this region were limited by small sample size, poor statistical methodology, population stratification and variable disease definition. Although more recent studies have improved study design, investigators are still challenged by the complex patterns of l...

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Publication status:
Published

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Publisher copy:
10.1016/j.bpg.2004.01.003
Journal:
Best practice and research. Clinical gastroenterology More from this journal
Volume:
18
Issue:
3
Pages:
577-596
Publication date:
2004-06-01
DOI:
EISSN:
1532-1916
ISSN:
1521-6918
Language:
English
Keywords:
Pubs id:
pubs:135319
UUID:
uuid:d572619b-a050-475f-a8dc-e8aa761dcb9d
Local pid:
pubs:135319
Source identifiers:
135319
Deposit date:
2012-12-19

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