Using functional imaging to improve chemoradiotherapy outcomes in pancreatic and rectal cancer: moving towards a hypoxia targeting approach

Thesis

Biologically individualised, adaptive radiotherapy requires the integration of information obtained from molecular biomarkers with functional imaging to inform high-precision radiotherapy planning. Functional imaging allows the non-invasive assessment of heterogeneity in a number of tumour physiological characteristics, including the well-documented cause of chemoradioresistance, hypoxia. Functional imaging may be useful in treatment strategy selection and biological target volume (BTV) de...

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Authors: Wilson, J

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford