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SPECIFIC-INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIRODIKETOPIPERAZINE AT THE ANOMERIC POSITION OF GLUCOPYRANOSE

Abstract:
A key intermediate bicyclic lactone 6 allows control of the anomeric configuration of a spirodiketopiperazine of glucopyranose 5 which is a specific inhibitor of glycogen phosphorylase, showing no inhibition of α- and β-glucosidases, α- and β-galactosidases, β-N-acetylglucosaminidase, pectinase, xylanase or cellulase. © 1995.
Publication status:
Published

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Authors


GREGORIOU, M More by this author
JOHNSON, L More by this author
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Journal:
TETRAHEDRON LETTERS
Volume:
36
Issue:
45
Pages:
8291-8294
Publication date:
1995-11-06
DOI:
ISSN:
0040-4039
URN:
uuid:d54e26cf-199a-4d50-8d61-6830a54b5688
Source identifiers:
44902
Local pid:
pubs:44902

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