SPECIFIC-INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIRODIKETOPIPERAZINE AT THE ANOMERIC POSITION OF GLUCOPYRANOSE
- A key intermediate bicyclic lactone 6 allows control of the anomeric configuration of a spirodiketopiperazine of glucopyranose 5 which is a specific inhibitor of glycogen phosphorylase, showing no inhibition of α- and β-glucosidases, α- and β-galactosidases, β-N-acetylglucosaminidase, pectinase, xylanase or cellulase. © 1995.
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