Journal article icon

Journal article

RNA aptamers binding the double-stranded RNA-binding domain.

Abstract:

Specific RNA recognition of proteins containing the double-strand RNA-binding domain (dsRBD) is essential for several biological pathways such as ADAR-mediated adenosine deamination, localization of RNAs by Staufen, or RNA cleavage by RNAse III. Structural analysis has demonstrated the lack of base-specific interactions of dsRBDs with either a perfect RNA duplex or an RNA hairpin. We therefore asked whether in vitro selections performed in parallel with individual dsRBDs could yield RNAs that...

Expand abstract

Actions


Access Document


Publisher copy:
10.1261/rna.125506

Authors


Hallegger, M More by this author
Taschner, A More by this author
Jantsch, MF More by this author
Journal:
RNA (New York, N.Y.)
Volume:
12
Issue:
11
Pages:
1993-2004
Publication date:
2006-11-05
DOI:
EISSN:
1469-9001
ISSN:
1355-8382
URN:
uuid:d5444bbd-60eb-4753-a0c6-3a313fc6e1ee
Source identifiers:
334667
Local pid:
pubs:334667

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP