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Functional domains in dorsal striatum of the nonhuman primate are defined by the dynamic behavior of dopamine.

Abstract:

The dorsal striatum comprises a continuum of distinct functional domains, limbic, associative, and sensorimotor. In the primate it exclusively subdivides further into two nuclei, the putamen and caudate. Dopamine (DA) transmission is differentially affected between these nuclei in neurodegenerative diseases such as Parkinson's and by psychostimulants such as cocaine. Because rodent systems can offer only limited insight into DA systems of the human brain, a fuller appreciation of DA transmiss...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
22
Issue:
13
Pages:
5705-5712
Publication date:
2002-07-05
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:d53df99b-c80f-4904-ba49-309752262002
Source identifiers:
113907
Local pid:
pubs:113907

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