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Neuraminidase inhibitors for influenza: a systematic review and meta-analysis of regulatory and mortality data

Abstract:

Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide.To (1) describe the potential benefits and harms of NIs for influenza in all age groups by reviewing all clinical study reports (CSRs) of published and unpublished randomised, placebo-controlled trials and regulatory comments; and (2) determine the effect of oseltamivir (Tamiflu(®), Roche) treatment on mortality...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3310/hta20420

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Department:
Oxford, MSD, Primary Care, Primary Care Health Sciences
Onakpoya, I More by this author
Del Mar, CB More by this author
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Health Technology Assessment Programme More from this funder
Publisher:
NIHR Health Technology Assessment Programme Publisher's website
Journal:
Health Technology Assessment Journal website
Volume:
20
Issue:
42
Publication date:
2016-05-05
Acceptance date:
2015-10-05
DOI:
ISSN:
1366-5278 and 2046-4924
Pubs id:
pubs:625057
URN:
uri:d537f860-2320-43d0-866c-6f786003677d
UUID:
uuid:d537f860-2320-43d0-866c-6f786003677d
Local pid:
pubs:625057
Language:
English
Keywords:

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