BACKGROUND: In 2015, high rates of microcephaly were reported in Northeast Brazil following the first South American Zika virus (ZIKV) outbreak. Reported microcephaly rates in other Zika-affected areas were significantly lower, suggesting alternate causes or the involvement of arboviral cofactors in exacerbating microcephaly rates.
METHODS AND FINDINGS: We merged data from multiple national reporting databases in Brazil to estimate exposure to 9 kno...Expand abstract
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- PLoS Medicine Journal website
- Article: e1002755
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- Brady et al.
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- © 2019 Brady et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births
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