Journal article icon

Journal article

Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation.

Abstract:

The eukaryotic cell cycle requires precise temporal coordination of the activities of hundreds of 'executor' proteins (EPs) involved in cell growth and division. Cyclin-dependent protein kinases (Cdks) play central roles in regulating the production, activation, inactivation and destruction of these EPs. From genome-scale data sets of budding yeast, we identify 126 EPs that are regulated by Cdk1 both through direct phosphorylation of the EP and through phosphorylation of the transcription fac...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/msb.2008.73

Authors


Expand authors...
Journal:
Molecular systems biology
Volume:
5
Pages:
236
Publication date:
2009-01-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292
Source identifiers:
100703
Language:
English
Keywords:
Pubs id:
pubs:100703
UUID:
uuid:d519e013-a68e-4f26-90a5-6ed02966698b
Local pid:
pubs:100703
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP