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Journal article

Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation.

Abstract:

The eukaryotic cell cycle requires precise temporal coordination of the activities of hundreds of 'executor' proteins (EPs) involved in cell growth and division. Cyclin-dependent protein kinases (Cdks) play central roles in regulating the production, activation, inactivation and destruction of these EPs. From genome-scale data sets of budding yeast, we identify 126 EPs that are regulated by Cdk1 both through direct phosphorylation of the EP and through phosphorylation of the transcription fac...

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Publication status:
Published

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Publisher copy:
10.1038/msb.2008.73

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Journal:
Molecular systems biology
Volume:
5
Pages:
236
Publication date:
2009-01-01
DOI:
EISSN:
1744-4292
ISSN:
1744-4292
URN:
uuid:d519e013-a68e-4f26-90a5-6ed02966698b
Source identifiers:
100703
Local pid:
pubs:100703

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