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Genomic modulators of the immune response

Abstract:

Our understanding of immunity has historically been informed by studying heritable mutations in both the adaptive and innate immune responses, including primary immunodeficiency and autoimmune diseases. Recent advances achieved through the application of genomic and epigenomic approaches are reshaping the study of immune dysfunction and opening up new avenues for therapeutic interventions. Moreover, applying genomic techniques to resolve functionally important genetic variation between indivi...

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Publisher copy:
10.1016/j.tig.2012.10.006

Authors


Knight, JC More by this author
Journal:
Trends in Genetics
Volume:
29
Issue:
2
Pages:
74-83
Publication date:
2013-02-05
DOI:
ISSN:
0168-9525
URN:
uuid:d501a120-26b4-444c-b904-44b0119ce48a
Source identifiers:
384710
Local pid:
pubs:384710

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