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Genomic modulators of the immune response

Abstract:

Our understanding of immunity has historically been informed by studying heritable mutations in both the adaptive and innate immune responses, including primary immunodeficiency and autoimmune diseases. Recent advances achieved through the application of genomic and epigenomic approaches are reshaping the study of immune dysfunction and opening up new avenues for therapeutic interventions. Moreover, applying genomic techniques to resolve functionally important genetic variation between indivi...

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Publisher copy:
10.1016/j.tig.2012.10.006

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Journal:
Trends in Genetics More from this journal
Volume:
29
Issue:
2
Pages:
74-83
Publication date:
2013-02-01
DOI:
ISSN:
0168-9525
Language:
English
Keywords:
Pubs id:
pubs:384710
UUID:
uuid:d501a120-26b4-444c-b904-44b0119ce48a
Local pid:
pubs:384710
Source identifiers:
384710
Deposit date:
2013-11-17

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