Thesis
Structural studies of peptide binding to chicken class I MHC molecules, the CD6-CD166 interaction and enzymes involved in bacterial sulfur metabolism
- Abstract:
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T cell activation is critical for the initiation of the adaptive immune response against both pathogens and malignant cells. This process depends on a complex set of finely tuned interactions, not only between the T cell receptor (TCR) and peptide-MHC complexes, but also between numerous accessory molecules. Chapter 2 of this thesis examines CD6, a transmembrane glycoprotein predominantly found on the surface of T cells, and its interaction with CD166, another transmembrane glycoprotein fo...
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Keywords:
- Subjects:
- UUID:
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uuid:d4fa5a1b-530b-4a10-8184-02742cfa34f6
- Deposit date:
- 2016-07-04
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Terms of use
- Copyright holder:
- Chappell, P; . Paul Elliott Chappell
- Copyright date:
- 2015
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