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Default mode network abnormalities in mesial temporal lobe epilepsy: a study combining fMRI and DTI.

Abstract:

Studies of in mesial temporal lobe epilepsy (mTLE) patients with hippocampal sclerosis (HS) have reported reductions in both functional and structural connectivity between hippocampal structures and adjacent brain regions. However, little is known about the connectivity among the default mode network (DMN) in mTLE. Here, we hypothesized that both functional and structural connectivity within the DMN were disturbed in mTLE. To test this hypothesis, functional magnetic resonance imaging (fMRI) ...

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Publisher copy:
10.1002/hbm.21076

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Journal:
Human brain mapping
Volume:
32
Issue:
6
Pages:
883-895
Publication date:
2011-06-05
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
URN:
uuid:d4f9a390-5cad-485b-bc17-213410896b36
Source identifiers:
364118
Local pid:
pubs:364118

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