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Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia.

Abstract:

The increasing prevalence of resistance to antimalarial drugs reduces options for malaria prophylaxis. Atovaquone/proguanil (Malarone; GlaxoSmithKline) has been >95% effective in preventing Plasmodium falciparum malaria in lifelong residents of areas of holoendemicity, but data from persons without clinical immunity or who are at risk for Plasmodium vivax malaria have not been described. We conducted a randomized, double-blinded study involving 297 people from areas of nonendemicity in Ind...

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Publication status:
Published

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Publisher copy:
10.1086/342578

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Fryauff, DJ More by this author
Sismadi, P More by this author
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Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume:
35
Issue:
7
Pages:
825-833
Publication date:
2002-10-05
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:d4b28fd2-2222-47e7-845d-12f2e00764f6
Source identifiers:
81603
Local pid:
pubs:81603

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