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Down-regulation of insular cortex responses to dyspnea and pain in asthma.

Abstract:

RATIONALE: Dyspnea is the impairing cardinal symptom of asthma but its accurate perception is also crucial for timely initiation of treatment. However, the underlying brain mechanisms of perceived dyspnea in patients with asthma are unknown. OBJECTIVES: To study brain mechanisms of dyspnea in asthma. METHODS: By using functional magnetic resonance imaging we compared the neuronal responses to experimentally induced dyspnea in patients with asthma and healthy controls. These brain activations...

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Publisher copy:
10.1164/rccm.200902-0300oc

Authors


von Leupoldt, A More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Baumann, HJ More by this author
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Journal:
American journal of respiratory and critical care medicine
Volume:
180
Issue:
3
Pages:
232-238
Publication date:
2009-08-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:d4793355-e6b2-4899-8219-cbf34312596b
Source identifiers:
241295
Local pid:
pubs:241295

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