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Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis.

Abstract:

Multiple candidate biomarkers for amyotrophic lateral sclerosis (ALS) have emerged across a range of platforms. Replication of results, however, has been absent in all but a few cases, and the range of control samples has been limited. If progress toward clinical translation is to continue, the specific biomarker needs of ALS, which differ from those of other neurodegenerative disorders, as well as the challenges inherent to longitudinal ALS biomarker cohorts, must be understood. Appropriate ...

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Publication status:
Published

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Publisher copy:
10.1002/mus.24470

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Benatar, M More by this author
Publisher:
John Wiley and Sons Inc.
Journal:
Muscle and nerve
Volume:
51
Issue:
1
Pages:
14-18
Publication date:
2015-01-05
DOI:
EISSN:
1097-4598
ISSN:
0148-639X
URN:
uuid:d46c270f-cf58-4390-a003-be36629f0adc
Source identifiers:
486157
Local pid:
pubs:486157

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