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Journal article

From genomics to targeted treatment in haematological malignancies: a focus on acute myeloid leukaemia

Abstract:

The haematological malignancies are a heterogeneous group of neoplastic disorders, which lead to almost 10,000 deaths annually in the UK. Over the past 2 decades, there has been significant progress in our understanding of the pathological mechanisms underlying these cancers, accompanied by improvements in outcomes for some patients. In particular, advances in next-generation sequencing now make it possible to define the genetic lesions present in each patient, which has led to improved disea...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7861/clinmedicine.18-2-s47

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
More from this funder
Name:
National Institute for Health Research
Funding agency for:
Jakobsen, N
Publisher:
Royal College of Physicians
Journal:
Clinical Medicine More from this journal
Volume:
18
Issue:
S2
Pages:
s47-s53
Publication date:
2018-04-01
Acceptance date:
2017-07-01
DOI:
EISSN:
1473-4893
ISSN:
1470-2118
Keywords:
Pubs id:
pubs:729265
UUID:
uuid:d43e497e-7305-4b55-8c88-93da42247af8
Local pid:
pubs:729265
Source identifiers:
729265
Deposit date:
2017-09-18

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