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Journal article

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors.

Abstract:

Vascular development begins when mesodermal cells differentiate into endothelial cells, which then form primitive vessels. It has been hypothesized that endothelial-specific gene expression may be regulated combinatorially, but the transcriptional mechanisms governing specificity in vascular gene expression remain incompletely understood. Here, we identify a 44 bp transcriptional enhancer that is sufficient to direct expression specifically and exclusively to the developing vascular endotheli...

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Publication status:
Published

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Publisher copy:
10.1016/j.cell.2008.10.049

Authors


Meadows, SM More by this author
Minovitsky, S More by this author
Anderson, JP More by this author
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Journal:
Cell
Volume:
135
Issue:
6
Pages:
1053-1064
Publication date:
2008-12-05
DOI:
EISSN:
1097-4172
ISSN:
0092-8674
URN:
uuid:d436e603-0855-408e-8baa-0d80637e8f97
Source identifiers:
68051
Local pid:
pubs:68051

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