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Journal article

Autophagy in stem cells.

Abstract:

Autophagy is a highly conserved cellular process by which cytoplasmic components are sequestered in autophagosomes and delivered to lysosomes for degradation. As a major intracellular degradation and recycling pathway, autophagy is crucial for maintaining cellular homeostasis as well as remodeling during normal development, and dysfunctions in autophagy have been associated with a variety of pathologies including cancer, inflammatory bowel disease and neurodegenerative disease. Stem cells are...

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Publication status:
Published

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Publisher copy:
10.4161/auto.24132

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Molecular Medicine
Prescott, M More by this author
Menendez, JA More by this author
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Journal:
Autophagy
Volume:
9
Issue:
6
Pages:
830-849
Publication date:
2013-06-05
DOI:
EISSN:
1554-8635
ISSN:
1554-8627
URN:
uuid:d431f5dc-b6e6-495c-8278-ddac4d2c44f9
Source identifiers:
426572
Local pid:
pubs:426572

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