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Electroanalytical exploitation of quinone-thiol interactions: application to the selective determination of cysteine.

Abstract:

Square wave voltammetry was applied to the detection of cysteine through the use of an indirect assay that exploits the reaction of the thiol with a quinone indicator. Voltammetric discrimination between unreacted quinone and the corresponding quinone-cysteine adduct is possible with clear resolution of the latter peak providing a linear response from 5 to 47 microM. The selectivity of the approach was assessed with no interference from cystine, lysine, paracetamol or 4-aminophenol. The respo...

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Publication status:
Published

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Publisher copy:
10.1039/b008616i

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Analyst More from this journal
Volume:
126
Issue:
3
Pages:
353-357
Publication date:
2001-03-01
DOI:
EISSN:
1364-5528
ISSN:
0003-2654
Language:
English
Keywords:
Pubs id:
pubs:31859
UUID:
uuid:d40e6be9-f1ab-469a-9d03-812ed6207d26
Local pid:
pubs:31859
Source identifiers:
31859
Deposit date:
2012-12-19

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