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Journal article

Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis.

Abstract:

BACKGROUND: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord. OBJECTIVE: To assess the frequency of AQP4-Ab in patients with optic neuritis (ON), and to investigate the prognostic implications of AQP4-Ab seropositivity in such patients. PATIENTS AND METHODS: AQP4-Ab serum levels were determined in 224...

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Publication status:
Published

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Publisher copy:
10.1016/j.jns.2010.07.011

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
Journal of the neurological sciences
Volume:
298
Issue:
1-2
Pages:
158-162
Publication date:
2010-11-05
DOI:
EISSN:
1878-5883
ISSN:
0022-510X
URN:
uuid:d3f11ff1-cbdc-4a70-8e5e-ff7a98e82db4
Source identifiers:
241296
Local pid:
pubs:241296

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