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Journal article

Synergistic effect of low dose cyclosporine A and human interleukin 10 overexpression on acute rejection in rat lung allotransplantation.

Abstract:

OBJECTIVE: Electroporation mediated transfer of plasmid DNA into peripheral muscle results in high transfection efficiency. The aim of this study was to investigate the effect of gene transfer of human IL-10 (hIL-10) into the tibialis anterior muscle (MTA) in combination with low dose Cyclosporine A (CsA) on acute rejection of lung allografts in the rat. METHODS: Lung allotransplantation was performed from male BN donor to male Fisher F344 rats. Gene transfer was achieved by intramuscular in...

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Publication status:
Published

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Publisher copy:
10.1016/j.ejcts.2005.03.008

Authors


Gazdhar, A More by this author
Stammberger, U More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Clinical Lab Sciences, Biomedical Research Centre
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Journal:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Volume:
27
Issue:
6
Pages:
1030-1035
Publication date:
2005-06-05
DOI:
EISSN:
1873-734X
ISSN:
1010-7940
URN:
uuid:d3c3f032-3a17-4fb4-bfcf-78c16c8b0f85
Source identifiers:
246415
Local pid:
pubs:246415

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