Ultrasound assessment of articular cartilage: analysis of the frequency profile of reflected signals from naturally and artificially degraded samples.

Journal article

This article investigates in vitro the hypothesis that the frequency profile of ultrasound reflections may be used to characterize degradation and osteoarthritic progression in articular cartilage, irrespective of the effects of transducer orientation. To this end, ultrasound echoes were taken in the time domain from the articular surface and osteochondral junction of normal, collagen meshwork-disrupted, proteoglycan-depleted, and osteoarthritic samples, converted to the frequency domain by f...

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Authors: Brown, C; Hughes, S; Crawford, R; Oloyede, A

• Journal: Connective tissue research
• Volume: 48
• Issue: 6
• Pages: 277-285
• Publication date: 2007-01-01
• DOI: 10.1080/03008200701692354
• EISSN: 1607-8438
• ISSN: 0300-8207
• Language: English
• Keywords: Trypsin; Osteoarthritis; Male; Patella; Proteoglycans; Cartilage, Articular; Collagenases; Cattle; Animals