Journal article icon

Journal article

A concise total synthesis of (+/-)-1-epiaustraline.

Abstract:
[reaction: see text] A concise total synthesis of 1-epiaustraline 3 is described that utilizes a diastereoselective Birch reduction of an electron-deficient pyrrole and a chelation-controlled vinyl Grignard addition to an aldehyde to introduce the C7 stereocenter. The C1 and C2 stereocenters were set through an OsO(4)-catalyzed dihydroxylation.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/ol049397s

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Organic letters
Volume:
6
Issue:
12
Pages:
2003-2006
Publication date:
2004-06-05
DOI:
EISSN:
1523-7052
ISSN:
1523-7060
URN:
uuid:d3a6e5ec-171d-4beb-a8a6-7579b75da96e
Source identifiers:
32734
Local pid:
pubs:32734

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP