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Journal article

The femoral stem pump in cemented hip arthroplasty: an in vitro model.

Abstract:
The presence of an intra-articular pump has been proposed as a central mechanism in the process of osteolysis and aseptic loosening of hip arthroplasty. It is not known if this pump exists and its mechanism remains uncharacterised. This study describes a new in vitro model of a cemented femoral stem in which cement/stem interface fluid pressures can be reliably measured under dynamic loads simulating stair climbing. A stem pump mechanism was found that generates both positive and negative clinically significant pressures (mean pressure ranges 5000-17,000 Pa). The timing of pressure peaks on the anterior and posterior aspects of the stem were in anti-phase, giving rise to oscillatory pressure gradients and potentially generating oscillatory fluid flows during the simulated physiological load cycle. The pump mechanism was shown to occur at the interface of a newly implanted polished double-tapered stem and emphasizes the importance of a complete mantle to protect the femoral bone from the raised fluid pressures.
Publication status:
Published

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Publisher copy:
10.1016/j.medengphy.2007.12.011

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author


Journal:
Medical engineering and physics More from this journal
Volume:
30
Issue:
8
Pages:
1042-1048
Publication date:
2008-10-01
DOI:
EISSN:
1873-4030
ISSN:
1350-4533


Language:
English
Keywords:
Pubs id:
pubs:62553
UUID:
uuid:d3a45f2f-e4aa-48b2-990c-af02302ec299
Local pid:
pubs:62553
Source identifiers:
62553
Deposit date:
2012-12-19

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